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H01 Phase I Dose-Finding Trials: Practical Application of New Designs For Statisticians

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H01 Phase I Dose-Finding Trials: Practical Application of New Designs For Statisticians
Dates of Event
24th October 2017 – 25th October 2017
Last Booking Date for this Event
16th October 2017
Description

In this one and a half day course you will learn about the types of novel model-based designs that are increasingly used in phase I dose-finding studies, such as the Continual Reassessment Method, and how these approaches could lead to more efficient clinical trials.

Although there have been individual lectures on specific methodological/theoretical aspects of these phase I designs within conferences or as seminars, the course in October will provide a good introduction to the key concepts of model-based designs (half day), and focus on practical application (one day). Using real trial examples, within a computer class, you will learn how to use R-software to: evaluate different designs; identify an appropriate approach for a trial; develop parts of a trial protocol; and analyse the data.

The sessions will be led by researchers and trial statisticians with extensive experience in designing, conducting and analysing dose-finding trials, both in oncology and non-oncology settings.

www.ctc.ucl.ac.uk

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